Rotigotine

A drug used in the treatment of Parkinson’s Disease, Restless Legs Syndrome and Periodic Limb Movement Disorder.  It is a dopamine agonist stimulating dopamine receptors in the brain. It is only available in a trans dermal patch form.  Major and common side effects include constipation, nausea, dizziness, excess sleepiness and Impulse Control Disorder.  In Restless Legs Syndrome it can cause augmentation (worsening) of symptoms over time.  It has the longest window of clinical effect of all the dopamine agonist.

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